What is GLP?
GLP was introduced in the 1970s after several high-profile cases of data manipulation in toxicology studies. The goal was to ensure that safety data submitted to regulators could be trusted. Under GLP, every study must have a written protocol, qualified personnel, validated equipment, and complete, traceable records of all activities. GLP applies mainly to non-clinical work such as pharmacology, toxicology, and environmental studies. It focuses on study integrity rather than business management. The principles ensure that test results are accurate, reproducible, and fully auditable by regulatory authorities. For biotechs preparing to move a compound into clinical trials, working with a GLP-compliant lab can make the difference between smooth regulatory approval and costly delays.What is ISO?
The International Organization for Standardization (ISO) develops global standards that define best practice in manufacturing, testing, and quality management. For research and analytical laboratories, the most relevant are:
ISO certification demonstrates that an organisation has documented, controlled processes for how it operates. It also shows a commitment to continuous improvement through internal audits and external reviews. For clients outsourcing scientific services, an ISO-certified provider signals professionalism, reliability, and accountability.
How do ISO and GLP complement each other?
Although ISO and GLP have different scopes, they overlap in their focus on traceability and control. ISO frameworks emphasise organisation-wide systems, while GLP focuses on study-specific conduct. A laboratory that operates under both can deliver not only consistent data but also efficient project management and strong documentation. For example, a GLP study performed in an ISO-certified facility benefits from the broader quality management system that governs staff training, supplier management, and document control. The result is higher confidence in both the data and the processes that produced it.Why scientists should care
For researchers, these standards may sometimes feel like administrative hurdles, but in reality they protect the integrity of science. Following structured quality systems reduces the likelihood of experimental errors, improves reproducibility, and makes collaboration easier. When everyone uses common documentation and approval methods, multi-partner projects run more smoothly. Compliance also builds credibility with investors and regulators. Data generated under GLP or ISO conditions is more likely to be accepted in submissions and due diligence reviews. Even internal R&D programs benefit, because quality-driven processes promote better decision-making and clearer records of how results were achieved.Building a culture of quality
Adopting ISO or GLP principles is not just about passing audits. It is about building a culture where accuracy, transparency, and accountability are valued at every level. Training staff in documentation practices, maintaining calibrated equipment, and reviewing procedures regularly are practical steps that foster this culture. For biotech companies partnering with external laboratories, checking for ISO or GLP compliance should be part of the selection process. These frameworks ensure that your outsourced data will stand up to regulatory and scientific scrutiny. In the long run, that trust in your results is what drives progress, partnerships, and investment in innovation.Providers list their Quality and Compliance Accreditations on their Storefront, and Members can filter and compare Providers by them. See the Glossary for definitions of each accreditation.
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